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Home / Primary Antibodies / Polyclonal Antibodies

Anti-BMP4 Antibody Picoband®

SKU : BHA21001293

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Mfr.No.	A00321, A00321-10ug, A00321-Biotin, A00321-Cy3, A00321-Dylight488, A00321-Dylight550, A00321-Dylight594, A00321-FITC, A00321-HRP, A00321-APC, A00321-PE, A00321-iFluor647, A00321-carrier-free
Alternative Names	bone morphogenetic protein 4
Background	Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. It is found on chromosome 14q22-q23. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alteative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-BMP4 Antibody Picoband® catalog # A00321. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle i
Host	Rabbit
Immunogen Region	E. coli-derived human BMP4 recombinant protein (Position: S293-R408).
Isotype	Rabbit IgG
Molecular Weight	22 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Bone morphogenetic protein 4; BMP-4; Bone morphogenetic protein 2B; BMP-2B; BMP4; BMP2B, DVR4;
Tissue Specificity	Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	BMP4: P12644
Gene Id	652
Gene Name	BMP4
Subcellular Location	Secreted, extracellular space, extracellular matrix.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml<br>

Reference	1. Knöchel S, Dillinger K, Köster M, Knöchel W (November 2001). "Structure and expression of Xenopus tropicalis BMP-2 and BMP-4 genes". Mech. Dev. 109 (1): 7982.<br /><br />2. Oida S, Iimura T, Maruoka Y, Takeda K, Sasaki S (Nov 1995). "Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library". DNA Seq 5 (5): 2735.<br /><br />3. van den Wijngaard A, Weghuis DO, Boersma CJ, van Zoelen EJ, Geurts van Kessel A, Olijve W (Nov 1995). "Fine mapping of the human bone morphogenetic protein-4 gene (BMP4) to chromosome 14q22-q23 by in situ hybridization". Genomics 27 (3): 55960.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001293-1	A00321	100 ug	-	$370		Add to Cart
BHA21001293-2	A00321-10ug	10 ug	Sample	$99		Add to Cart
BHA21001293-3	A00321-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001293-4	A00321-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001293-5	A00321-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001293-6	A00321-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001293-7	A00321-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001293-8	A00321-FITC	100 ug	FITC	$570		Add to Cart
BHA21001293-9	A00321-HRP	100 ug	HRP	$570		Add to Cart
BHA21001293-10	A00321-APC	100 ug	APC	$670		Add to Cart
BHA21001293-11	A00321-PE	100 ug	PE	$670		Add to Cart
BHA21001293-12	A00321-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001293-13	A00321-carrier-free	100 ug	carrier-free	$370		Add to Cart

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