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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Beta 2 Microglobulin/B2M Antibody Picoband®

SKU : BHA21003514

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Mfr.No.	A00456-1, A00456-1-10ug, A00456-1-Biotin, A00456-1-Cy3, A00456-1-Dylight488, A00456-1-Dylight550, A00456-1-Dylight594, A00456-1-FITC, A00456-1-HRP, A00456-1-APC, A00456-1-PE, A00456-1-iFluor647, A00456-1-carrier-free
Alternative Names	Neutrophil gelatinase-associated lipocalin
Background	Beta-2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the beta-2-microglobulin protein is encoded by the B2M gene. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Beta 2 Microglobulin/B2M Antibody Antibody Picoband® catalog # A00456-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial e
Host	Rabbit
Immunogen Region	E.coli-derived human Beta 2 Microglobulin recombinant protein (Position: Q22-M119). Human Beta 2 Microglobulin shares 69.4% and 74.5% amino acid (aa) sequence identity with mouse and rat Beta 2 Microglobulin, respectively.
Isotype	Rabbit IgG
Molecular Weight	14 kDa
Reactivity	Human
Reconstitution	Adding 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Tissue Specificity	Detected in lung, spleen, uterus, vagina and epididymis. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P61769
Gene Id	567
Gene Name	B2M
Subcellular Location	Secreted . Upon binding to the SLC22A17 (24p3R) receptor, it is intealized.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry(Paraffin-embedded Section), 0.5-1 ug/ml, Human, By Heat Immunocytochemistry/Immunofluorescence, 2ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human ELISA(Cap), 1-5 ug/ml, Human

Reference	1. Güssow D, Rein R, Ginjaar I, Hochstenbach F, Seemann G, Kottman A, Ploegh HL (1 November 1987). "The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit". J. Immunol. 139 (9): 31328. 2. Munshi NC, Longo DL, Anderson KC (2011). "Chapter 111: Plasma Cell Disorders". In Loscalzo J, Longo DL, Fauci AS, Dennis LK, Hauser SL. Harrison's Principles of Inteal Medicine (18th ed.). McGraw-Hill Professional. pp. 93644. 3. Pignone M, Nicoll D; McPhee SJ (2004). Pocket guide to diagnostic tests (4th ed.). New York: McGraw-Hill. p. 191. ISBN 0-07-141184-4.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003514-1	A00456-1	-	100 ug	$370		Add to Cart
BHA21003514-2	A00456-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003514-3	A00456-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003514-4	A00456-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003514-5	A00456-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003514-6	A00456-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003514-7	A00456-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003514-8	A00456-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003514-9	A00456-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003514-10	A00456-1-APC	APC	100 ug	$670		Add to Cart
BHA21003514-11	A00456-1-PE	PE	100 ug	$670		Add to Cart
BHA21003514-12	A00456-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003514-13	A00456-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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