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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Bcl2 alpha Antibody Picoband®

SKU : BHA21006578

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Mfr.No.	RP1003, RP1003-10ug, RP1003-Biotin, RP1003-Cy3, RP1003-Dylight488, RP1003-Dylight550, RP1003-Dylight594, RP1003-FITC, RP1003-HRP, RP1003-APC, RP1003-PE, RP1003-iFluor647, RP1003-carrier-free
Alternative Names	Apoptosis regulator Bcl-2
Background	Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t (14;18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Bcl2 alpha Antibody catalog # RP1003. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. In
Host	Rabbit
Immunogen Region	E. coli-derived human BCL-2 recombinant protein (Position: M1-D211).
Isotype	Rabbit IgG
Molecular Weight	26 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Apoptosis regulator Bcl-2;BCL2;
Tissue Specificity	Expressed in a variety of tissues.
Note	Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify "Carrier Free" or "No BSA" in your order note.

Uniprot	P10415
Gene Name	BCL2
Sequence	Belongs to the Bcl-2 family.
Subcellular Location	Mitochondrion outer membrane ; Single-pass membrane protein . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	ELISA, 0.1-0.5ug/ml, -<br>Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Hockenbery, D.; Nunez, G.; Milliman, C.; Schreiber, R. D.; Korsmeyer, S. J. : Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336, 1990.<br /><br />2. Ngan, B.-Y.; Chen-Levy, Z.; Weiss, L. M.; Wake, R. A.; Cleary, M. L. : Expression in non-Hodgkin's lymphoma of the BCL-2 protein associated with the t(14;18) chromosomal translocation. New Eng. J. Med. 318: 1638-1644, 1988.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006578-1	RP1003	-	100 ug	$370		Add to Cart
BHA21006578-2	RP1003-10ug	Sample	10 ug	$99		Add to Cart
BHA21006578-3	RP1003-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006578-4	RP1003-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006578-5	RP1003-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006578-6	RP1003-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006578-7	RP1003-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006578-8	RP1003-FITC	FITC	100 ug	$570		Add to Cart
BHA21006578-9	RP1003-HRP	HRP	100 ug	$570		Add to Cart
BHA21006578-10	RP1003-APC	APC	100 ug	$670		Add to Cart
BHA21006578-11	RP1003-PE	PE	100 ug	$670		Add to Cart
BHA21006578-12	RP1003-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006578-13	RP1003-carrier-free	carrier-free	100 ug	$370		Add to Cart

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