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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Bcl-XS/BCL2L1 Antibody Picoband®

SKU : BHA21006690

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Mfr.No.	PA1232, PA1232-10ug, PA1232-Biotin, PA1232-Cy3, PA1232-Dylight488, PA1232-Dylight550, PA1232-Dylight594, PA1232-FITC, PA1232-HRP, PA1232-APC, PA1232-PE, PA1232-iFluor647, PA1232-carrier-free
Alternative Names	Bcl-2-like protein 1
Background	Bcl-xS is the second mRNA species of Bcl-x protein, which encodes a protein that inhibits the ability of bcl-2 to enhance the survival of growth factor-deprived cells. In vivo, bcl-xS mRNA is expressed at high levels in cells that undergo a high rate of tuover, such as developing lymphocytes. Apoptosis was associated with increased protein expression of Bcl-X/S, an early marker of apoptosis, and release of cytochrome c into the cytosol of infected HB cells.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Bcl-XS/BCL2L1 Antibody catalog # PA1232. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial memb
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human Bcl-XS, different from the related rat and mouse sequences by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	19 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Bcl-2-like protein 1;Bcl2-L-1;Apoptosis regulator Bcl-X;BCL2L1;BCL2L, BCLX;
Tissue Specificity	Bcl-X (S) is expressed at high levels in cells that undergo a high rate of tuover, such as developing lymphocytes. In contrast, Bcl-X (L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q07817
Gene Name	BCL2L1
Sequence	Belongs to the Bcl-2 family.
Subcellular Location	Isoform Bcl-X (L): Mitochondrion inner membrane . Mitochondrion outer membrane . Mitochondrion matrix . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Cytoplasm, cytosol . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane ; Single-pass membrane protein ; Cytoplasmic side . After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner (By similarity). Localizes to the centrosome when phosphorylated at Ser-49. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat <br>Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1. "Entrez Gene: BCL2L1 BCL2-like 1".<br /><br />2. Boise LH, González-García M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nuñez G, Thompson CB (Aug 1993). "bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death". Cell 74(4): 597608.<br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006690-1	PA1232	-	100 ug	$370		Add to Cart
BHA21006690-2	PA1232-10ug	Sample	10 ug	$99		Add to Cart
BHA21006690-3	PA1232-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006690-4	PA1232-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006690-5	PA1232-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006690-6	PA1232-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006690-7	PA1232-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006690-8	PA1232-FITC	FITC	100 ug	$570		Add to Cart
BHA21006690-9	PA1232-HRP	HRP	100 ug	$570		Add to Cart
BHA21006690-10	PA1232-APC	APC	100 ug	$670		Add to Cart
BHA21006690-11	PA1232-PE	PE	100 ug	$670		Add to Cart
BHA21006690-12	PA1232-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006690-13	PA1232-carrier-free	carrier-free	100 ug	$370		Add to Cart

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