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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ATP7A Antibody Picoband®

SKU : BHA21006390

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Mfr.No.	A01085-1, A01085-1-10ug, A01085-1-Biotin, A01085-1-Cy3, A01085-1-Dylight488, A01085-1-Dylight550, A01085-1-Dylight594, A01085-1-FITC, A01085-1-HRP, A01085-1-APC, A01085-1-PE, A01085-1-iFluor647, A01085-1-carrier-free
Alternative Names	ATPase copper transporting alpha
Background	ATP7A, also known as Menkes' protein (MNK), is a copper-transporting P-type ATPase which uses the energy arising from ATP hydrolysis to transport Cu(I) across cell membranes. This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital ho syndrome. Alteatively-spliced transcript variants have been observed.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-ATP7A Antibody Picoband® catalog # A01085-1. Tested in WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human ATP7A, which shares 79.2% amino acid (aa) sequence identity with both mouse and rat ATP7A.
Isotype	Rabbit IgG
Molecular Weight	163 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	ATP7A; MC1; MNK; Copper-transporting ATPase 1; EC 7.2.2.8; Copper pump 1; Menkes disease-associated protein
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q04656
Gene Id	538
Gene Name	ATP7A

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Cecchi, C., Biasotto, M., Tosi, M., Avner, P. The mottled mouse as a model for human Menkes disease: identification of mutations in the Atp7a gene. Hum. Molec. Genet. 6: 425-433, 1997. Note: Erratum: Hum. Molec. Genet. 6: 829 only, 1997. 2. Chelly, J., Tumer, Z., Tonnesen, T., Petterson, A., Ishikawa-Brush, Y., Tommerup, N., Ho, N., Monaco, A. P. Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein. Nature Genet. 3: 14-19, 1993. 3. Christodoulou, J., Danks, D. M., Sarkar, B., Baerlocher, K. E., Casey, R., Ho, N., Tumer, Z., Clarke, J. T. R. Early treatment of Menkes disease with parenteral cooper (sic)-histidine: long-term follow-up of four treated patients. Am. J. Med. Genet. 76: 154-164, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006390-1	A01085-1	-	100 ug	$370		Add to Cart
BHA21006390-2	A01085-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21006390-3	A01085-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006390-4	A01085-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006390-5	A01085-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006390-6	A01085-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006390-7	A01085-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006390-8	A01085-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21006390-9	A01085-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21006390-10	A01085-1-APC	APC	100 ug	$670		Add to Cart
BHA21006390-11	A01085-1-PE	PE	100 ug	$670		Add to Cart
BHA21006390-12	A01085-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006390-13	A01085-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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