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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ATP5G1,2,3/ATP5MC1,2,3 Antibody Picoband®

SKU : BHA21002178

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Mfr.No.	A09735, A09735-10ug, A09735-Biotin, A09735-Cy3, A09735-Dylight488, A09735-Dylight550, A09735-Dylight594, A09735-FITC, A09735-HRP, A09735-APC, A09735-PE, A09735-iFluor647, A09735-carrier-free
Alternative Names	ATP synthase membrane subunit c locus 1,2,3
Background	The ATP5MC1 gene is one of three human paralogs that encode membrane subunit c of the mitochondrial ATP synthase. It is mapped to 17q21.32. This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alteatively spliced transcript variants encoding the same protein have been identified.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ATP5G1,2,3/ATP5MC1,2,3 Antibody Picoband® catalog # A09735. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two
Host	Rabbit
Immunogen Region	E.coli-derived human ATP5F1/ATP5MC1 recombinant protein (Position: D62-L113).
Isotype	Rabbit IgG
Molecular Weight	10-14 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	ATP synthase F (0) complex subunit C1,2,3, mitochondrial; ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 1,2,3; ATP synthase proteolipid P1; ATP synthase proton-transporting mitochondrial F (0) complex subunit C1,2,3; ATPase protein 9; ATPase subunit c; ATP5MC1,2,3; ATP5G1,2,3
Tissue Specificity	Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	ATP5MC1: P05496
Gene Id	516
Gene Name	ATP5MC1
Subcellular Location	Mitochondrion membrane. Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat<, By Heat<br> Immunofluorescence, 2ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Dyer, M. R., Walker, J. E. Sequences of members of the human gene family for the c subunit of mitochondrial ATP synthase. Biochem. J. 293: 51-64, 1993. <br /><br />2. Walker, J. E. Determination of the structures of respiratory enzyme complexes from mammalian mitochondria. Biochim. Biophys. Acta 1271: 221-227, 1995. <br /><br />3. Yan, W. L., Leer, T. J., Haines, J. L., Gusella, J. F. Sequence analysis and mapping of a novel human mitochondrial ATP synthase subunit 9 cDNA (ATP5G3). Genomics 24: 375-377, 1994.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002178-1	A09735	-	100 ug	$370		Add to Cart
BHA21002178-2	A09735-10ug	Sample	10 ug	$99		Add to Cart
BHA21002178-3	A09735-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002178-4	A09735-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002178-5	A09735-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002178-6	A09735-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002178-7	A09735-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002178-8	A09735-FITC	FITC	100 ug	$570		Add to Cart
BHA21002178-9	A09735-HRP	HRP	100 ug	$570		Add to Cart
BHA21002178-10	A09735-APC	APC	100 ug	$670		Add to Cart
BHA21002178-11	A09735-PE	PE	100 ug	$670		Add to Cart
BHA21002178-12	A09735-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002178-13	A09735-carrier-free	carrier-free	100 ug	$370		Add to Cart

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