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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ATP1A4 Antibody Picoband®

SKU : BHA21005964

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Mfr.No.	A09005, A09005-10ug, A09005-Biotin, A09005-Cy3, A09005-Dylight488, A09005-Dylight550, A09005-Dylight594, A09005-FITC, A09005-HRP, A09005-APC, A09005-PE, A09005-iFluor647, A09005-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	Sodium/potassium-transporting ATPase subunit alpha-4 is an enzyme that in humans is encoded by the ATP1A4 gene. The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alteatively spliced transcript variants encoding different isoforms have been identified.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-ATP1A4 Antibody Picoband® catalog # A11289-2. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human ATP1A4 recombinant protein (Position: K45-Q680). Human ATP1A4 shares 84.2% and 84.1% amino acid (aa) sequence identity with mouse and rat ATP1A4, respectively.
Isotype	IgG
Molecular Weight	100 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q13733
Gene Id	480
Gene Name	ATP1A4
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Buetow, K. H., Nishimura, D., Nakamura, Y., Jiang, O., Murray, J. C. A detailed multipoint gene map of chromosome 1q. Genomics 8: 13-21, 1990. Note: Erratum: Genomics 9: 564 only, 1991. <br /><br />2. Jimenez, T., McDermott, J. P., Sanchez, G., Blanco, G. Na,K-ATPase alpha-4 isoform is essential for sperm fertility. Proc. Nat. Acad. Sci. 108: 644-649, 2011.<br /><br />3. Keryanov, S., Gardner, K. L. Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4. Gene 292: 151-166, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005964-1	A09005	-	100 ug	$370		Add to Cart
BHA21005964-2	A09005-10ug	Sample	10 ug	$99		Add to Cart
BHA21005964-3	A09005-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005964-4	A09005-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005964-5	A09005-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005964-6	A09005-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005964-7	A09005-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005964-8	A09005-FITC	FITC	100 ug	$570		Add to Cart
BHA21005964-9	A09005-HRP	HRP	100 ug	$570		Add to Cart
BHA21005964-10	A09005-APC	APC	100 ug	$670		Add to Cart
BHA21005964-11	A09005-PE	PE	100 ug	$670		Add to Cart
BHA21005964-12	A09005-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005964-13	A09005-carrier-free	carrier-free	100 ug	$370		Add to Cart

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