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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ARID2 Antibody Picoband®

SKU : BHA21002176

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Mfr.No.	A05064, A05064-10ug, A05064-Biotin, A05064-Cy3, A05064-Dylight488, A05064-Dylight550, A05064-Dylight594, A05064-FITC, A05064-HRP, A05064-APC, A05064-PE, A05064-iFluor647, A05064-carrier-free
Alternative Names	AT-rich interaction domain 2
Background	AT-rich interactive domain-containing protein 2 (ARID2) is a protein that in humans is encoded by the ARID2 gene. It is mapped to 12q12. This gene encodes a member of the AT-rich interactive domain (ARID)-containing family of DNA-binding proteins. Members of the ARID family have roles in embryonic patteing, cell lineage gene regulation, cell cycle control, transcriptional regulation and chromatin structure modification. This protein functions as a subunit of the polybromo- and BRG1-associated factor or PBAF (SWI/SNF-B) chromatin remodeling complex which facilitates ligand-dependent transcriptional activation by nuclear receptors. Mutations in this gene are associated with hepatocellular carcinomas. A pseudogene of this gene is found on chromosome1.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ARID2 Antibody Picoband® catalog # A05064. Tested in IP, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting th
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human ARID2, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	245 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	AT-rich interactive domain-containing protein 2; ARID domain-containing protein 2; BRG1-associated factor 200; BAF200; Zinc finger protein with activation potential; Zipzap/p200; ARID2; BAF200; KIAA1557
Tissue Specificity	Highly expressed in heart.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q68CP9
Gene Id	196528
Gene Name	ARID2
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IP, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunoprecipitation, 0.5-2 ug/ml<br>

Reference	1. Biankin, A. V., Waddell, N., Kassahn, K. S., Gingras, M.-C., Muthuswamy, L. B., Johns, A. L., Miller, D. K., Wilson, P. J., Patch, A.-M., Wu, J., Chang, D. K., Cowley, M. J., and 116 others. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 491: 399-405, 2012.<br /><br />2. Bramswig, N. C., Caluseriu, O., Ludecke, H.-J., Bolduc, F. V., Noel, N. C. L., Wieland, T., Surowy, H. M., Christen, H.-J., Engels, H., Strom, T. M., Wieczorek, D. Heterozygosity for ARID2 loss-of-function mutations in individuals with a Coffin-Siris syndrome-like phenotype. Hum. Genet. 136: 297-305, 2017.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002176-1	A05064	-	100 ug	$370		Add to Cart
BHA21002176-2	A05064-10ug	Sample	10 ug	$99		Add to Cart
BHA21002176-3	A05064-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002176-4	A05064-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002176-5	A05064-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002176-6	A05064-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002176-7	A05064-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002176-8	A05064-FITC	FITC	100 ug	$570		Add to Cart
BHA21002176-9	A05064-HRP	HRP	100 ug	$570		Add to Cart
BHA21002176-10	A05064-APC	APC	100 ug	$670		Add to Cart
BHA21002176-11	A05064-PE	PE	100 ug	$670		Add to Cart
BHA21002176-12	A05064-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002176-13	A05064-carrier-free	carrier-free	100 ug	$370		Add to Cart

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