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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Aquaporin 6/AQP6 Antibody Picoband®

SKU : BHA21001161

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Mfr.No.	A10607, A10607-10ug, A10607-Biotin, A10607-Cy3, A10607-Dylight488, A10607-Dylight550, A10607-Dylight594, A10607-FITC, A10607-HRP, A10607-APC, A10607-PE, A10607-iFluor647, A10607-carrier-free
Alternative Names	Aquaporin-6
Background	Aquaporin 6, kidney specific is a protein in humans that is encoded by the AQP6 gene. The aquaporins (AQPs) are a family of water-transporting proteins that facilitate osmotically driven water movement across cell plasma membranes. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Aquaporin 6/AQP6 Antibody Picoband® catalog # A10607. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 6, different from the related mouse and rat sequences by fourteen amino acids.
Isotype	Rabbit IgG
Molecular Weight	29 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Aquaporin-6;AQP-6;Aquaporin-2-like;Kidney-specific aquaporin;hKID;AQP6;AQP2L;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q13520
Gene Id	363
Gene Name	AQP6
Subcellular Location	Cytoplasmic vesicle membrane ; Multi-pass membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, By Heat <br>Weste blot, 0.1-0.5ug/ml, Mouse, Rat, Human<br>

Reference	1. "Entrez Gene: Aquaporin 6, kidney specific". <br /><br />2. Liu, K., Kozono, D., Kato, Y., Agre, P., Hazama, A., Yasui, M. Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution. Proc. Nat. Acad. Sci. 102: 2192-2197, 2005. <br /><br />3. Ma, T., Yang, B., Umenishi, F., Verkman, A. S. Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13. Genomics 43: 387-389, 1997.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001161-1	A10607	100 ug	-	$370		Add to Cart
BHA21001161-2	A10607-10ug	10 ug	Sample	$99		Add to Cart
BHA21001161-3	A10607-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001161-4	A10607-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001161-5	A10607-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001161-6	A10607-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001161-7	A10607-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001161-8	A10607-FITC	100 ug	FITC	$570		Add to Cart
BHA21001161-9	A10607-HRP	100 ug	HRP	$570		Add to Cart
BHA21001161-10	A10607-APC	100 ug	APC	$670		Add to Cart
BHA21001161-11	A10607-PE	100 ug	PE	$670		Add to Cart
BHA21001161-12	A10607-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001161-13	A10607-carrier-free	100 ug	carrier-free	$370		Add to Cart

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