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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Aquaporin 5/AQP5 Antibody Picoband®

SKU : BHA21006689

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Mfr.No.	PA1230, PA1230-10ug, PA1230-Biotin, PA1230-Cy3, PA1230-Dylight488, PA1230-Dylight550, PA1230-Dylight594, PA1230-FITC, PA1230-HRP, PA1230-APC, PA1230-PE, PA1230-iFluor647, PA1230-carrier-free
Alternative Names	Aquaporin-5
Background	Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins (AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0 (MIP) in lens fiber, AQP1 in coea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in coeal and lacrimal gland epithelia. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Aquaporin 5/AQP5 Antibody catalog # PA1230. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of mouse AQP5, identical to the related rat sequence.
Isotype	Rabbit IgG
Molecular Weight	62 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Aquaporin-5;AQP-5;Aqp5;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q9WTY4
Gene Name	AQP5
Subcellular Location	Membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Rat, Mouse, By Heat<br>Weste blot, 0.1-0.5ug/ml, Rat, Mouse<br>

Reference	1. Verkman AS (2003). "Role of aquaporin water channels in eye function.". Exp. Eye Res. 76 (2): 13743.<br /><br />2. Ma T, Yang B, Umenishi F, Verkman AS (1997). "Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13.". Genomics 43 (3): 3879.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006689-1	PA1230	-	100 ug	$370		Add to Cart
BHA21006689-2	PA1230-10ug	Sample	10 ug	$99		Add to Cart
BHA21006689-3	PA1230-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006689-4	PA1230-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006689-5	PA1230-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006689-6	PA1230-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006689-7	PA1230-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006689-8	PA1230-FITC	FITC	100 ug	$570		Add to Cart
BHA21006689-9	PA1230-HRP	HRP	100 ug	$570		Add to Cart
BHA21006689-10	PA1230-APC	APC	100 ug	$670		Add to Cart
BHA21006689-11	PA1230-PE	PE	100 ug	$670		Add to Cart
BHA21006689-12	PA1230-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006689-13	PA1230-carrier-free	carrier-free	100 ug	$370		Add to Cart

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