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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Aquaporin 3/Aqp3 Antibody Picoband®

SKU : BHA21001157

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Mfr.No.	A02181, A02181-10ug, A02181-Biotin, A02181-Cy3, A02181-Dylight488, A02181-Dylight550, A02181-Dylight594, A02181-FITC, A02181-HRP, A02181-APC, A02181-PE, A02181-iFluor647, A02181-carrier-free
Alternative Names	Aquaporin-3
Background	This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alteative splicing of this gene results in multiple transcript variants encoding different isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Aquaporin 3/Aqp3 Antibody Picoband® catalog # A02181. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum coeum) and epidermal glycerol content. Involved in skin hydra
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of mouse Aquaporin 3, different from the related human sequence by three amino acids, and from the related rat sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	32 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Aquaporin-3;AQP-3;Aquaglyceroporin-3;Aqp3;
Tissue Specificity	Renal medulla and colon. Predominantly in the inner medulla. Expressed in basal layer of epidermal keratinocytes.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q8R2N1
Gene Id	11828
Gene Name	Aqp3
Subcellular Location	Membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat, Human<br>

Reference	1. Dibas AI, Mia AJ, Yorio T (1998). "Aquaporins (water channels): role in vasopressin-activated water transport". Proc. Soc. Exp. Biol. Med. 219 (3): 18399.<br /><br />2. Roudier N, Ripoche P, Gane P, Le Pennec PY, Daniels G, Cartron JP, Bailly P (2002). "AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL". J. Biol. Chem. 277 (48): 458549.<br /><br />3. Sasaki S, Ishibashi K, Marumo F (1998). "Aquaporin-2 and -3: representatives of two subgroups of the aquaporin family colocalized in the kidney collecting duct". Annu. Rev. Physiol. 60: 199220.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001157-1	A02181	100 ug	-	$370		Add to Cart
BHA21001157-2	A02181-10ug	10 ug	Sample	$99		Add to Cart
BHA21001157-3	A02181-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001157-4	A02181-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001157-5	A02181-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001157-6	A02181-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001157-7	A02181-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001157-8	A02181-FITC	100 ug	FITC	$570		Add to Cart
BHA21001157-9	A02181-HRP	100 ug	HRP	$570		Add to Cart
BHA21001157-10	A02181-APC	100 ug	APC	$670		Add to Cart
BHA21001157-11	A02181-PE	100 ug	PE	$670		Add to Cart
BHA21001157-12	A02181-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001157-13	A02181-carrier-free	100 ug	carrier-free	$370		Add to Cart

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