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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Aquaporin 3/AQP3 Antibody Picoband®

SKU : BHA21006833

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Mfr.No.	PA1488, PA1488-10ug, PA1488-Biotin, PA1488-Cy3, PA1488-Dylight488, PA1488-Dylight550, PA1488-Dylight594, PA1488-FITC, PA1488-HRP, PA1488-APC, PA1488-PE, PA1488-iFluor647, PA1488-carrier-free
Alternative Names	Aquaporin-3
Background	This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alteative splicing of this gene results in multiple transcript variants encoding different isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Aquaporin 3/AQP3 Antibody catalog # PA1488. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum coeum) and epidermal glycerol content. Involved in skin hydra
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 3, different from the related rat and mouse sequences by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	32-36 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Aquaporin-3;AQP-3;Aquaglyceroporin-3;AQP3;
Tissue Specificity	Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q92482
Gene Name	AQP3
Sequence	Belongs to the MIP/aquaporin (TC 1.A.8) family.
Subcellular Location	Basolateral cell membrane; Multi-pass membrane protein. In collecting ducts of kidney.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat<br>Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Rat, Mouse, By Heat <br>Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br>Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human

Reference	1. Dibas AI, Mia AJ, Yorio T (1998). "Aquaporins (water channels): role in vasopressin-activated water transport". Proc. Soc. Exp. Biol. Med. 219 (3): 18399.<br /><br />2. Roudier N, Ripoche P, Gane P, Le Pennec PY, Daniels G, Cartron JP, Bailly P (2002). "AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL". J. Biol. Chem. 277 (48): 458549.<br /><br />3. Sasaki S, Ishibashi K, Marumo F (1998). "Aquaporin-2 and -3: representatives of two subgroups of the aquaporin family colocalized in the kidney collecting duct". Annu. Rev. Physiol. 60: 199220.<br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006833-1	PA1488	-	100 ug	$370		Add to Cart
BHA21006833-2	PA1488-10ug	Sample	10 ug	$99		Add to Cart
BHA21006833-3	PA1488-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006833-4	PA1488-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006833-5	PA1488-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006833-6	PA1488-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006833-7	PA1488-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006833-8	PA1488-FITC	FITC	100 ug	$570		Add to Cart
BHA21006833-9	PA1488-HRP	HRP	100 ug	$570		Add to Cart
BHA21006833-10	PA1488-APC	APC	100 ug	$670		Add to Cart
BHA21006833-11	PA1488-PE	PE	100 ug	$670		Add to Cart
BHA21006833-12	PA1488-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006833-13	PA1488-carrier-free	carrier-free	100 ug	$370		Add to Cart

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