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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Aquaporin 10/AQP10 Antibody Picoband®

SKU : BHA21007302

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Mfr.No.	PA2095, PA2095-10ug, PA2095-Biotin, PA2095-Cy3, PA2095-Dylight488, PA2095-Dylight550, PA2095-Dylight594, PA2095-FITC, PA2095-HRP, PA2095-APC, PA2095-PE, PA2095-iFluor647, PA2095-carrier-free
Alternative Names	Aquaporin-10
Background	AQP10 was identified in human small intestine. This gene encoded a 264-amino-acid protein with high sequence identity with AQP3 (53%), 9 (52%), and 7 (43%). These AQPs constitute one subfamily of AQP family that is differentiated from the other subfamily of AQP (AQP0, 1, 2, 4, 5, 6, and 8) by sequence homology. Northe blot analysis revealed expression of a 2.3-kb AQP10 transcript in jejunum but not liver. RNase protection analysis detected nearly exclusive expression in duodenum and jejunum. In situ hybridization analysis demonstrated highest expression of AQP10 in absorptive epithelial cells at the tips of villi in the jejunum. SDS-PAGE analysis showed expression of a 28-kD AQP10 protein, similar to its predicted size as well as to that of the other AQPs. Functional analysis indicated that cells expressing AQP10 are permeable to relatively low amounts of water, but, unlike AQP3, AQP7, and AQP9, are not permeable to urea or glycerol.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Aquaporin 10/AQP10 Antibody catalog # PA2095. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 10.
Isotype	Rabbit IgG
Molecular Weight	31 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Aquaporin-10;AQP-10;Aquaglyceroporin-10;Small intestine aquaporin;AQP10;
Tissue Specificity	Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q96PS8
Gene Name	AQP10
Subcellular Location	Membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Hatakeyama, S., Yoshida, Y., Tani, T., Koyama, Y., Nihei, K., Ohshiro, K., Kamiie, J.-I., Yaoita, E., Suda, T., Hatakeyama, K., Yamamoto, T. Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum. Biochem. Biophys. Res. Commun. 287: 814-819, 2001.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007302-1	PA2095	-	100 ug	$370		Add to Cart
BHA21007302-2	PA2095-10ug	Sample	10 ug	$99		Add to Cart
BHA21007302-3	PA2095-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007302-4	PA2095-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007302-5	PA2095-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007302-6	PA2095-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007302-7	PA2095-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007302-8	PA2095-FITC	FITC	100 ug	$570		Add to Cart
BHA21007302-9	PA2095-HRP	HRP	100 ug	$570		Add to Cart
BHA21007302-10	PA2095-APC	APC	100 ug	$670		Add to Cart
BHA21007302-11	PA2095-PE	PE	100 ug	$670		Add to Cart
BHA21007302-12	PA2095-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007302-13	PA2095-carrier-free	carrier-free	100 ug	$370		Add to Cart

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