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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Apelin/APLN Antibody

SKU : BHA21004106

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Mfr.No.	A02075-1, A02075-1-10ug, A02075-1-Biotin, A02075-1-Cy3, A02075-1-Dylight488, A02075-1-Dylight550, A02075-1-Dylight594, A02075-1-FITC, A02075-1-HRP, A02075-1-APC, A02075-1-PE, A02075-1-iFluor647, A02075-1-carrier-free
Alternative Names	deleted in azoospermia like
Background	Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The apelin gene to Xq25-q26.3 based on sequence similarity between the apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Apelin/APLN Antibody Picoband® catalog # A02075-1. Tested in ELISA, IHC applications. This antibody reacts with Human.
Function	RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key t
Host	Rabbit
Immunogen Region	E.coli-derived human Apelin/APLN recombinant protein (Position: S24-F77).
Isotype	Rabbit IgG
Molecular Weight	41 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Deleted in azoospermia-like; DAZ homolog; DAZ-like autosomal; Deleted in azoospermia-like 1; SPGY-like-autosomal; DAZL; DAZH; DAZL1; DAZLA; SPGYLA
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9ULZ1
Gene Id	8862
Gene Name	APLN
Subcellular Location	Nucleus. Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	IHC, ELISA
Description	Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Cayabyab, M., Hinuma, S., Farzan, M., Choe, H., Fukusumi, S., Kitada, C., Nishizawa, N., Hosoya, M., Nishimura, O., Messele, T., Pollakis, G., Goudsmit, J., Fujino, M., Sodroski, J. Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.J. Virol. 74: 11972-11976, 2000.<br /><br />2. Chen, M. M., Ashley, E. A., Deng, D. X. F., Tsalenko, A., Deng, A., Tabibiazar, R., Ben-Dor, A., Fenster, B., Yang, E., King, J. Y., Fowler, M., Robbins, R., Johnson, F. L., Bruhn, L., McDonagh, T., Dargie, H., Yakhini, Z., Tsao, P. S., Quertermous, T.Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction.Circulation 108: 1432-1439, 2003.<br /><br />3. De Mota, N., Reaux-Le Goazigo, A., El Messari, S., Chartrel, N., Roesch, D., Dujardin, C., Kordon, C., Vaudry, H., Moos, F., Llorens-Cortes, C. Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release.Proc. Nat. Acad. Sci. 101: 10464-10469, 2004.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004106-1	A02075-1	-	100 ug	$370		Add to Cart
BHA21004106-2	A02075-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21004106-3	A02075-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004106-4	A02075-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004106-5	A02075-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004106-6	A02075-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004106-7	A02075-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004106-8	A02075-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21004106-9	A02075-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21004106-10	A02075-1-APC	APC	100 ug	$670		Add to Cart
BHA21004106-11	A02075-1-PE	PE	100 ug	$670		Add to Cart
BHA21004106-12	A02075-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004106-13	A02075-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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