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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Annexin V/ANXA5 Antibody Picoband®

SKU : BHA21007504

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Mfr.No.	PB9044, PB9044-10ug, PB9044-Biotin, PB9044-Cy3, PB9044-Dylight488, PB9044-Dylight550, PB9044-Dylight594, PB9044-FITC, PB9044-HRP, PB9044-APC, PB9044-PE, PB9044-iFluor647, PB9044-carrier-free
Alternative Names	Annexin A5
Background	Annexin A5 (or annexin V) is a cellular protein in the annexin group. It is mapped to 4q27. Annexin A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. This protein is an anticoagulant protein, it can form a shield around negatively-charged phospholipid molecules, the formation of an annexin A5 shield blocks the entry of phospholipids into coagulation (clotting) reactions. And Annexin A5 can also act as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Annexin V/ANXA5 Antibody Picoband® catalog # PB9044. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	This protein is an anticoagulant protein that acts as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Host	Rabbit
Immunogen Region	E.coli-derived human Annexin V recombinant protein (Position: A2-D320). Human Annexin V shares 94% and 92% amino acid (aa) sequences identity with mouse and rat Annexin V, respectively.
Isotype	Rabbit IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Annexin A5;Anchorin CII;Annexin V;Annexin-5;Calphobindin I;CBP-I;Endonexin II;Lipocortin V;Placental anticoagulant protein 4;PP4;Placental anticoagulant protein I;PAP-I;Thromboplastin inhibitor;Vascular anticoagulant-alpha;VAC-alpha;ANXA5;ANX5, ENX2, PP4;
Tissue Specificity	Expressed in all cell types so far analyzed.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P08758
Gene Id	308
Gene Name	ANXA5
Sequence	Belongs to the annexin family.
Subcellular Location	Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Localizes within both nucleus and cytoplasm of proliferative primary myoblasts and mostly within the nucleus of differentiated primary myoblasts. By virtue of the N-terminal PH domain, is recruited to sites of the plasma membrane containing increased PI (3,4,5)P3 or PI (3,4)P2, cell membrane targeting is also facilitared by interaction with CLIP3.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, IHC-F, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Human, Rat, - Immunofluorescence, 2ug/ml, Human Immunocytochemistry/Immunofluorescence, 2ug/ml, Human, Rat Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. Bogdanova, N., Horst, J., Chlystun, M., Croucher, P. J. P., Nebel, A., Bohring, A., Todorova, A., Schreiber, S., Gerke, V., Krawczak, M., Markoff, A. A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy loss.Hum. Molec. Genet. 16: 573-578, 2007. 2. Demange, P., Voges, D., Benz, J., Liemann, S., Gottig, P., Berendes, R., Burger, A., Huber, R. Annexin V: the key to understanding ion selectivity and voltage regulation Trends Biochem. Sci. 19: 272-276, 1994. 3. Sofiadis A, Becker S, Hellman U, Hultin-Rosenberg L, Dinets A, Hulchiy M, Zedenius J, Wallin G, Foukakis T, Höög A, Auer G, Lehtiö J, Larsson C. (April 2012). "Proteomic profiling of follicular and papillary thyroid tumors.". Eur J Endocrinol.. 166 (4): 65767.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007504-1	PB9044	-	100 ug	$370		Add to Cart
BHA21007504-2	PB9044-10ug	Sample	10 ug	$99		Add to Cart
BHA21007504-3	PB9044-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007504-4	PB9044-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007504-5	PB9044-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007504-6	PB9044-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007504-7	PB9044-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007504-8	PB9044-FITC	FITC	100 ug	$570		Add to Cart
BHA21007504-9	PB9044-HRP	HRP	100 ug	$570		Add to Cart
BHA21007504-10	PB9044-APC	APC	100 ug	$670		Add to Cart
BHA21007504-11	PB9044-PE	PE	100 ug	$670		Add to Cart
BHA21007504-12	PB9044-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007504-13	PB9044-carrier-free	carrier-free	100 ug	$370		Add to Cart

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