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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Angiotensinogen/AGT Antibody Picoband®

SKU : BHA21001066

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Mfr.No.	A02103-1, A02103-1-10ug, A02103-1-Biotin, A02103-1-Cy3, A02103-1-Dylight488, A02103-1-Dylight550, A02103-1-Dylight594, A02103-1-FITC, A02103-1-HRP, A02103-1-APC, A02103-1-PE, A02103-1-iFluor647, A02103-1-carrier-free
Alternative Names	Angiotensinogen
Background	AGT (ANGIOTENSINOGEN), also called SERPINA8, is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Angiotensinogen/AGT Antibody Picoband® catalog # A02103-1. Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
Host	Rabbit
Immunogen Region	E.coli-derived mouse Angiotensinogen recombinant protein (Position: D25-A115). Mouse Angiotensinogen shares 62.2% and 87.9% amino acid (aa) sequence identity with human and rat Angiotensinogen, respectively.
Isotype	Rabbit IgG
Molecular Weight	53-55 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Angiotensinogen;Serpin A8;Angiotensin-1;Angiotensin 1-10;Angiotensin I;Ang I;Angiotensin-2;Angiotensin 1-8;Angiotensin II;Ang II;Angiotensin-3;Angiotensin 2-8;Angiotensin III;Ang III;Des-Asp(1)-angiotensin II;Angiotensin-4;Angiotensin 3-8;Angiotensin IV;Ang IV;Angiotensin 1-9;Angiotensin 1-7;Angiotensin 1-5;Angiotensin 1-4;Agt;Serpina8;
Tissue Specificity	Expressed by the liver and secreted in plasma.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P11859
Gene Id	183
Gene Name	Agt
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, By Heat <br>Weste blot, 0.1-0.5ug/ml, Mouse<br>

Reference	1. Abonia, J. P., Abel, K. J., Eddy, R. L., Elliott, R. W., Chapman, V. M., Shows, T. B., Gross, K. W. Linkage of Agt and Actsk-1 to distal mouse chromosome 8 loci: a new conserved linkage. Mammalian Genome 4: 25-32, 1993.<br /><br />2. Arakawa, K., Minohara, A., Yamada, J., Nakamura, M. Enzymatic degradation and electrophoresis of human angiotensin I. Biochim. Biophys. Acta 168: 106-112, 1968.<br /><br />3. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 12469.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001066-1	A02103-1	100 ug	-	$370		Add to Cart
BHA21001066-2	A02103-1-10ug	10 ug	Sample	$99		Add to Cart
BHA21001066-3	A02103-1-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001066-4	A02103-1-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001066-5	A02103-1-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001066-6	A02103-1-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001066-7	A02103-1-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001066-8	A02103-1-FITC	100 ug	FITC	$570		Add to Cart
BHA21001066-9	A02103-1-HRP	100 ug	HRP	$570		Add to Cart
BHA21001066-10	A02103-1-APC	100 ug	APC	$670		Add to Cart
BHA21001066-11	A02103-1-PE	100 ug	PE	$670		Add to Cart
BHA21001066-12	A02103-1-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001066-13	A02103-1-carrier-free	100 ug	carrier-free	$370		Add to Cart

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