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Home / Primary Antibodies / Polyclonal Antibodies

Anti-AMOTL2 Antibody Picoband®

SKU : BHA21001404

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Mfr.No.	A06852, A06852-10ug, A06852-Biotin, A06852-Cy3, A06852-Dylight488, A06852-Dylight550, A06852-Dylight594, A06852-FITC, A06852-HRP, A06852-APC, A06852-PE, A06852-iFluor647, A06852-carrier-free
Alternative Names	angiomotin like 2
Background	Angiomotin-like protein 2 is a protein that in humans is encoded by the AMOTL2 gene. Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). It mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alteative splicing results in multiple transcript variants of this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-AMOTL2 Antibody Picoband® catalog # A06852. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and henc
Host	Rabbit
Immunogen Region	E. coli-derived human AMOTL2 recombinant protein (Position: A401-Q480).
Isotype	Rabbit IgG
Molecular Weight	95 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Angiomotin-like protein 2; Leman coiled-coil protein; LCCP; AMOTL2; KIAA0989
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q9Y2J4
Gene Id	51421
Gene Name	AMOTL2
Subcellular Location	Recycling endosome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Li, Z., Wang, Y., Zhang, M., Xu, P., Huang, H., Wu, D., Meng, A. The Amotl2 gene inhibits Wnt/B-catenin signaling and regulates embryonic development in zebrafish. J. Biol. Chem. 287: 13005-13015, 2012. <br /><br />2. Wang, Y., Li, Z., Xu, P., Huang, L., Tong, J., Huang, H., Meng, A. Angiomotin-like2 gene (amotl2) is required for migration and proliferation of endothelial cells during angiogenesis. J. Biol. Chem. 286: 41095-41104, 2011.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001404-1	A06852	100 ug	-	$370		Add to Cart
BHA21001404-2	A06852-10ug	10 ug	Sample	$99		Add to Cart
BHA21001404-3	A06852-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001404-4	A06852-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001404-5	A06852-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001404-6	A06852-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001404-7	A06852-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001404-8	A06852-FITC	100 ug	FITC	$570		Add to Cart
BHA21001404-9	A06852-HRP	100 ug	HRP	$570		Add to Cart
BHA21001404-10	A06852-APC	100 ug	APC	$670		Add to Cart
BHA21001404-11	A06852-PE	100 ug	PE	$670		Add to Cart
BHA21001404-12	A06852-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001404-13	A06852-carrier-free	100 ug	carrier-free	$370		Add to Cart

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