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Home / Primary Antibodies / Polyclonal Antibodies

Anti-alpha 1 Fetoprotein/AFP Antibody Picoband®

SKU : BHA21000001

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Mfr.No.	PB9090, PB9090-10ug, PB9090-Biotin, PB9090-Cy3, PB9090-Dylight488, PB9090-Dylight550, PB9090-Dylight594, PB9090-FITC, PB9090-HRP, PB9090-APC, PB9090-PE, PB9090-iFluor647, PB9090-carrier-free
Alternative Names	Alpha-fetoprotein
Background	AFP, also called Alpha-fetoprotein; alpha-fetoprotein, is a protein that in humans is encoded by the AFP gene. It is mapped to 4q13.3. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. In rodents AFP binds estradiol to prevent the transport of this hormone across the placenta to the fetus. The main function of this is to prevent the virilization of female fetuses. Moreover, it has an important role as a diagnostic marker, especially in certain tumors and liver diseases of childhood. AFP is also used to test the potential usefulness of plasma alpha fetoprotein determination as a diagnostic marker in biliary atresia, hepatitis, and yolk sac derived tumours.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-alpha 1 Fetoprotein/AFP Antibody Picoband® catalog # PB9090. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Host	Rabbit
Immunogen Region	E.coli-derived human AFP recombinant protein (Position: Q378-V609). Human AFP shares 71% and 73% amino acid (aa) sequences identity with mouse and rat AFP, respectively.
Isotype	Rabbit IgG
Molecular Weight	69 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Alpha-fetoprotein;Alpha-1-fetoprotein;Alpha-fetoglobulin;AFP;HPAFP;
Tissue Specificity	Plasma. Synthesized by the fetal liver and yolk sac.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P02771
Gene Id	174
Gene Name	AFP
Sequence	Belongs to the ALB/AFP/VDB family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat

Reference	1. Carter CS (2002). "Neuroendocrinology of sexual behavior in the female". In Becker JB. Behavioral Endocrinology. Cambridge, Mass: MIT Press. pp.88-89. ISBN 0-262-52321-3 2. Bader D, Riskin A, Vafsi O, Tamir A, Peskin B, Israel N, Merksamer R, Dar H, David M (November 2004). "Alpha-fetoprotein in the early neonatal period--a large study and review of the literature". Clin. Chim. Acta 349 (1-2): 1523. 3. Blair JI, Carachi R, Gupta R, Sim FG, McAllister EJ, Weston R (April 1987). "Plasma alpha fetoprotein reference ranges in infancy: effect of prematurity". Arch. Dis. Child. 62 (4): 3629.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21000001-1	PB9090	-	100 ug	$370		Add to Cart
BHA21000001-2	PB9090-10ug	Sample	10 ug	$99		Add to Cart
BHA21000001-3	PB9090-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21000001-4	PB9090-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21000001-5	PB9090-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21000001-6	PB9090-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21000001-7	PB9090-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21000001-8	PB9090-FITC	FITC	100 ug	$570		Add to Cart
BHA21000001-9	PB9090-HRP	HRP	100 ug	$570		Add to Cart
BHA21000001-10	PB9090-APC	APC	100 ug	$670		Add to Cart
BHA21000001-11	PB9090-PE	PE	100 ug	$670		Add to Cart
BHA21000001-12	PB9090-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21000001-13	PB9090-carrier-free	carrier-free	100 ug	$370		Add to Cart

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