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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ALG3 Antibody Picoband®

SKU : BHA21004990

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Mfr.No.	A04688, A04688-10ug, A04688-Biotin, A04688-Cy3, A04688-Dylight488, A04688-Dylight550, A04688-Dylight594, A04688-FITC, A04688-HRP, A04688-APC, A04688-PE, A04688-iFluor647, A04688-carrier-free
Alternative Names	growth arrest and DNA damage inducible gamma
Background	Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase is an enzyme that, in humans, is encoded by the ALG3 gene. This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ALG3 Antibody Picoband® catalog # A04688. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Host	Rabbit
Immunogen Region	E.coli-derived human ALG3 recombinant protein (Position: I61-H438).
Isotype	Rabbit IgG
Molecular Weight	50-55 kDa
Reactivity	Human, Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Growth arrest and DNA damage-inducible protein GADD45 gamma; Cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein; DDIT-2; GADD45G; CR6; DDIT2
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q92685
Gene Id	10195
Gene Name	ALG3

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Denecke, J., Kranz, C., Kemming, D., Koch, H.-G., Marquardt, T. An activated 5-prime cryptic splice site in the human ALG3 gene generates a premature termination codon insensitive to nonsense-mediated mRNA decay in a new case of congenital disorder of glycosylation type Id (CDG-Id). Hum. Mutat. 23: 477-486, 2004. 2. Denecke, J., Kranz, C., von Kleist-Retzow, J. C., Bosse, K., Herkenrath, P., Debus, O., Harms, E., Marquardt, T. Congenital disorder of glycosylation type Id: clinical phenotype, molecular analysis, prenatal diagnosis, and glycosylation of fetal proteins. Pediat. Res. 58: 248-253, 2005. 3. Koer, C., Knauer, R., Stephani, U., Marquardt, T., Lehle, L., von Figura, K. Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase. EMBO J. 18: 6816-6822, 1999.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004990-1	A04688	-	100 ug	$370		Add to Cart
BHA21004990-2	A04688-10ug	Sample	10 ug	$99		Add to Cart
BHA21004990-3	A04688-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004990-4	A04688-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004990-5	A04688-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004990-6	A04688-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004990-7	A04688-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004990-8	A04688-FITC	FITC	100 ug	$570		Add to Cart
BHA21004990-9	A04688-HRP	HRP	100 ug	$570		Add to Cart
BHA21004990-10	A04688-APC	APC	100 ug	$670		Add to Cart
BHA21004990-11	A04688-PE	PE	100 ug	$670		Add to Cart
BHA21004990-12	A04688-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004990-13	A04688-carrier-free	carrier-free	100 ug	$370		Add to Cart

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