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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Adam28 Antibody Picoband®

SKU : BHA21002491

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Mfr.No.	A06873-2, A06873-2-10ug, A06873-2-Biotin, A06873-2-Cy3, A06873-2-Dylight488, A06873-2-Dylight550, A06873-2-Dylight594, A06873-2-FITC, A06873-2-HRP, A06873-2-APC, A06873-2-PE, A06873-2-iFluor647, A06873-2-carrier-free
Alternative Names	ADAM metallopeptidase domain 28
Background	Disintegrin and metalloproteinase domain-containing protein 28 is an enzyme that in humans is encoded by the ADAM28 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. And this gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Adam28 Antibody Picoband® catalog # A06873-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
Host	Rabbit
Immunogen Region	E.coli-derived rat Adam28 recombinant protein (Position: K26-K195).
Isotype	Rabbit IgG
Molecular Weight	87 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Disintegrin and metalloproteinase domain-containing protein 28;ADAM 28;3.4.24.-;Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II;eMDC II;Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L;MDC-L;ADAM28;ADAM23, MDCL;
Tissue Specificity	Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	E9PTQ3
Gene Id	290344
Gene Name	ADAM28
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IHC, WB
Description	Weste blot, 0.25-0.5ug/ml, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Mouse<br> ELISA, 0.1-0.5ug/ml,<br>

Reference	1. Bates, E. E. M., Fridman, W. H., Mueller, C. G. F. The ADAMDEC1 (decysin) gene structure: evolution by duplication in a metalloprotease gene cluster on chromosome 8p12. Immunogenetics 54: 96-105, 2002. <br /><br />2. Bridges, L. C., Tani, P. H., Hanson, K. R., Roberts, C. M., Judkins, M. B., Bowditch, R. D. The lymphocyte metalloprotease MDC-L (ADAM28) is a ligand for the integrin alpha-4/beta-1. J. Biol. Chem. 277: 3784-3792, 2002.<br /><br />3. Jury, J. A., Perry, A. C. F., Hall, L. Identification, sequence analysis and expression of transcripts encoding a putative metalloproteinase, eMDC II, in human and macaque epididymis. Molec. Hum. Reprod. 5: 1127-1134, 1999.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002491-1	A06873-2	-	100 ug	$370		Add to Cart
BHA21002491-2	A06873-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21002491-3	A06873-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002491-4	A06873-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002491-5	A06873-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002491-6	A06873-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002491-7	A06873-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002491-8	A06873-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21002491-9	A06873-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21002491-10	A06873-2-APC	APC	100 ug	$670		Add to Cart
BHA21002491-11	A06873-2-PE	PE	100 ug	$670		Add to Cart
BHA21002491-12	A06873-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002491-13	A06873-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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