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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ADAM2 Antibody Picoband®

SKU : BHA21007279

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Mfr.No.	PA2069, PA2069-10ug, PA2069-Biotin, PA2069-Cy3, PA2069-Dylight488, PA2069-Dylight550, PA2069-Dylight594, PA2069-FITC, PA2069-HRP, PA2069-APC, PA2069-PE, PA2069-iFluor647, PA2069-carrier-free
Alternative Names	Disintegrin and metalloproteinase domain-containing protein 2
Background	ADAM2 (A Disintegrin and Metalloproteinase Domain 2) , also known as FTNB or PH30, is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Burkin et al. (1997) used fluorescence in situ hybridization to map the FTNB gene to 8p11.2.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-ADAM2 Antibody catalog # PA2069. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane coul
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human ADAM2.
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Disintegrin and metalloproteinase domain-containing protein 2;ADAM 2;Cancer/testis antigen 15;CT15;Fertilin subunit beta;PH-30;PH30;PH30-beta;ADAM2;FTNB;
Tissue Specificity	Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q99965
Gene Name	ADAM2
Sequence	Contains 1 disintegrin domain.
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Gupta SK, Alves K, Palladino LO, Mark GE, Hollis GF (Aug 1996). "Molecular cloning of the human fertilin beta subunit". Biochem Biophys Res Commun 224 (2): 31826.<br /><br />2. Burkin, H. R., Burkin, D. J., Davey, P. M., Griffin, D. K., Affara, N. A. Mapping, sequence, and expression analysis of the human fertilin beta gene (FTNB). Genomics 40: 190-192, 1997.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007279-1	PA2069	-	100 ug	$370		Add to Cart
BHA21007279-2	PA2069-10ug	Sample	10 ug	$99		Add to Cart
BHA21007279-3	PA2069-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007279-4	PA2069-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007279-5	PA2069-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007279-6	PA2069-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007279-7	PA2069-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007279-8	PA2069-FITC	FITC	100 ug	$570		Add to Cart
BHA21007279-9	PA2069-HRP	HRP	100 ug	$570		Add to Cart
BHA21007279-10	PA2069-APC	APC	100 ug	$670		Add to Cart
BHA21007279-11	PA2069-PE	PE	100 ug	$670		Add to Cart
BHA21007279-12	PA2069-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007279-13	PA2069-carrier-free	carrier-free	100 ug	$370		Add to Cart

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