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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ACSL1 Antibody Picoband®

SKU : BHA21000930

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Mfr.No.	PB10025, PB10025-10ug, PB10025-Biotin, PB10025-Cy3, PB10025-Dylight488, PB10025-Dylight550, PB10025-Dylight594, PB10025-FITC, PB10025-HRP, PB10025-APC, PB10025-PE, PB10025-iFluor647, PB10025-carrier-free
Alternative Names	Long-chain-fatty-acid--CoA ligase 1
Background	Long-chain-fatty-acidCoA ligase 1 is an enzyme that in humans is encoded by the ACSL1 gene. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. This specific protein is most commonly found in mitochondria and peroxisomes.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-ACSL1 Antibody Picoband® catalog # PB10025. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
Host	Rabbit
Immunogen Region	E. coli-derived human ACSL1 recombinant protein (Position: D604-V698). Human ACSL1 shares 81.1% and 86.3% amino acid (aa) sequence identity with mouse and rat ACSL1, respectively.
Isotype	Rabbit IgG
Molecular Weight	78 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Long-chain-fatty-acid--CoA ligase 1;6.2.1.3;Acyl-CoA synthetase 1;ACS1;Long-chain acyl-CoA synthetase 1;LACS 1;Long-chain acyl-CoA synthetase 2;LACS 2;Long-chain fatty acid-CoA ligase 2;Palmitoyl-CoA ligase 1;Palmitoyl-CoA ligase 2;ACSL1;FACL1, FACL2, LACS, LACS1, LACS2;
Tissue Specificity	Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P33121
Gene Id	2180
Gene Name	ACSL1
Subcellular Location	Mitochondrion outer membrane ; Single-pass type III membrane protein . Peroxisome membrane ; Single-pass type III membrane protein . Microsome membrane ; Single-pass type III membrane protein . Endoplasmic reticulum membrane ; Single-pass type III membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Immunocytochemistry/Immunofluorescence, 5ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. Meloni I, Muscettola M, Raynaud M, Longo I, Bruttini M, Moizard MP, Gomot M, Chelly J, des Portes V, Fryns JP, Ropers HH, Magi B, Bellan C, Volpi N, Yntema HG, Lewis SE, Schaffer JE, Renieri A (Apr 2002). "FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation". Nature Genetics 30 (4): 43640. 2. Longo I, Frints SG, Fryns JP, Meloni I, Pescucci C, Ariani F, Borghgraef M, Raynaud M, Marynen P, Schwartz C, Renieri A, Froyen G (Jan 2003). "A third MRX family (MRX68) is the result of mutation in the long chain fatty acid-CoA ligase 4 (FACL4) gene: proposal of a rapid enzymatic assay for screening mentally retarded patients". Joual of Medical Genetics 40 (1): 117.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000930-1	PB10025	100 ug	-	$370		Add to Cart
BHA21000930-2	PB10025-10ug	10 ug	Sample	$99		Add to Cart
BHA21000930-3	PB10025-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000930-4	PB10025-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000930-5	PB10025-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000930-6	PB10025-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000930-7	PB10025-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000930-8	PB10025-FITC	100 ug	FITC	$570		Add to Cart
BHA21000930-9	PB10025-HRP	100 ug	HRP	$570		Add to Cart
BHA21000930-10	PB10025-APC	100 ug	APC	$670		Add to Cart
BHA21000930-11	PB10025-PE	100 ug	PE	$670		Add to Cart
BHA21000930-12	PB10025-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000930-13	PB10025-carrier-free	100 ug	carrier-free	$370		Add to Cart

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