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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ACE2 Antibody Picoband®

SKU : BHA21006072

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Mfr.No.	A00756-3, A00756-3-10ug, A00756-3-Biotin, A00756-3-Cy3, A00756-3-Dylight488, A00756-3-Dylight550, A00756-3-Dylight594, A00756-3-FITC, A00756-3-HRP, A00756-3-APC, A00756-3-PE, A00756-3-iFluor647, A00756-3-carrier-free
Background	The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible.
Clonality	Polyclonal
Description	Boster Bio Anti-ACE2 Antibody Picoband® catalog # A00756-3. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	E.coli-derived human ACE2 recombinant protein (Position: Q18-F314). Human ACE2 shares 80.5% and 80.8% amino acid (aa) sequence identity with mouse and rat ACE2, respectively.
Molecular Weight	120 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9BYF1
Gene Id	59272
Gene Name	ACE2

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Boehm, M., Nabel, E. G. Angiotensin-converting enzyme 2--a new cardiac regulator. New Eng. J. Med. 347: 1795-1797, 2002. 2. Crackower, M. A., Sarao, R., Oudit, G. Y., Yagil, C., Kozieradzki, I., Scanga, S. E., Oliveira-dos-Santos, A. J., da Costa, J., Zhang, L., Pei, Y., Scholey, J., Ferrario, C. M., Manoukian, A. S., Chappell, M. C., Backx, P. H., Yagil, Y., Penninger, J. M. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 417: 822-828, 2002. 3. Gurley, S. B., Allred, A., Le, T. H., Griffiths, R., Mao, L., Philip, N., Haystead, T. A., Donoghue, M., Breitbart, R. E., Acton, S. L., Rockman, H. A., Coffman, T. M. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. J. Clin. Invest. 116: 2218-2225, 2006.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006072-1	A00756-3	-	100 ug	$370		Add to Cart
BHA21006072-2	A00756-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21006072-3	A00756-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006072-4	A00756-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006072-5	A00756-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006072-6	A00756-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006072-7	A00756-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006072-8	A00756-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21006072-9	A00756-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21006072-10	A00756-3-APC	APC	100 ug	$670		Add to Cart
BHA21006072-11	A00756-3-PE	PE	100 ug	$670		Add to Cart
BHA21006072-12	A00756-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006072-13	A00756-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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