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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Abhd5 Antibody Picoband®

SKU : BHA21000926

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Mfr.No.	PB10021, PB10021-10ug, PB10021-Biotin, PB10021-Cy3, PB10021-Dylight488, PB10021-Dylight550, PB10021-Dylight594, PB10021-FITC, PB10021-HRP, PB10021-APC, PB10021-PE, PB10021-iFluor647, PB10021-carrier-free
Alternative Names	1-acylglycerol-3-phosphate O-acyltransferase ABHD5
Background	1-acylglycerol-3-phosphate O-acyltransferase ABHD5 is an enzyme that in humans is encoded by the ABHD5 gene. The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated withChanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Abhd5 Antibody Picoband® catalog # PB10021. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis (PubMed:18606822). May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 (PubMed:16679289). Involved in keratinocyte diff
Host	Rabbit
Immunogen Region	E. coli-derived human Abhd5 recombinant protein (Position: R169-D349). Human Abhd5 shares 96.7% amino acid (aa) sequence identity with both mouse and rat Abhd5.
Isotype	Rabbit IgG
Molecular Weight	43 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	1-acylglycerol-3-phosphate O-acyltransferase ABHD5;2.3.1.51;Abhydrolase domain-containing protein 5;Lipid droplet-binding protein CGI-58;ABHD5;NCIE2;CGI-58;
Tissue Specificity	Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q8WTS1
Gene Id	51099
Gene Name	ABHD5
Sequence	Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
Subcellular Location	Cytoplasm . Lipid droplet . Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, ICC, WB
Description	Immunocytochemistry/Immunofluorescence, 2ug/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Weste blot, 0.1-0.5ug/ml, Human, Rat

Reference	1. Ghosh AK, Ramakrishnan G, Chandramohan C, Rajasekharan R (Sep 2008). "CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid". The Joual of Biological Chemistry 283 (36): 2452533. 2. Skaes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A (Jun 2011). "A conditional knockout resource for the genome-wide study of mouse gene function". Nature 474 (7351): 337342.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000926-1	PB10021	100 ug	-	$370		Add to Cart
BHA21000926-2	PB10021-10ug	10 ug	Sample	$99		Add to Cart
BHA21000926-3	PB10021-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000926-4	PB10021-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000926-5	PB10021-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000926-6	PB10021-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000926-7	PB10021-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000926-8	PB10021-FITC	100 ug	FITC	$570		Add to Cart
BHA21000926-9	PB10021-HRP	100 ug	HRP	$570		Add to Cart
BHA21000926-10	PB10021-APC	100 ug	APC	$670		Add to Cart
BHA21000926-11	PB10021-PE	100 ug	PE	$670		Add to Cart
BHA21000926-12	PB10021-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000926-13	PB10021-carrier-free	100 ug	carrier-free	$370		Add to Cart

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