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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ABCB10 Antibody Picoband®

SKU : BHA21000877

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Mfr.No.	PB9971, PB9971-10ug, PB9971-Biotin, PB9971-Cy3, PB9971-Dylight488, PB9971-Dylight550, PB9971-Dylight594, PB9971-FITC, PB9971-HRP, PB9971-APC, PB9971-PE, PB9971-iFluor647, PB9971-carrier-free
Alternative Names	ATP-binding cassette sub-family B member 10, mitochondrial
Background	ABCB10, also known as M-ABC2, is expressed as a 60-kD nonglycosylated mitochondrial membrane protein. This ABCB10 gene is mapped to 1q42.13. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. And ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-ABCB10 Antibody Picoband® catalog # PB9971. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May mediate critical mitochondrial transport functions related to heme biosynthesis. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB10, different from the related mouse sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	79 kDa, 65 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	ATP-binding cassette sub-family B member 10, mitochondrial;ATP-binding cassette transporter 10;ABC transporter 10 protein;Mitochondrial ATP-binding cassette 2;M-ABC2;ABCB10;
Tissue Specificity	Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q9NRK6
Gene Id	23456
Gene Name	ABCB10
Subcellular Location	Mitochondrion inner membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat

Reference	1. Allikmets, R., Gerrard, B., Glavac, D., Ravnik-Glavac, M., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Modi, W., Dean, M.Characterization and mapping of three new mammalian ATP-binding transporter genes from an EST database. Mammalian Genome 6: 114-117, 1995. 2. Chen, W., Paradkar, P. N., Li, L., Pierce, E. L., Langer, N. B., Takahashi-Makise, N., Hyde, B. B., Shirihai, O. S., Ward, D. M., Kaplan, J., Paw, B. H. Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proc. Nat. Acad. Sci. 106: 16263-16268, 2009. 3. Zhang, F., Hogue, D. L., Liu, L., Fisher, C. L., Hui, D., Childs, S., Ling, V. M-ABC2, a new human mitochondrial ATP-binding cassette membrane protein. FEBS Lett. 478: 89-94, 2000.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000877-1	PB9971	100 ug	-	$370		Add to Cart
BHA21000877-2	PB9971-10ug	10 ug	Sample	$99		Add to Cart
BHA21000877-3	PB9971-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000877-4	PB9971-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000877-5	PB9971-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000877-6	PB9971-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000877-7	PB9971-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000877-8	PB9971-FITC	100 ug	FITC	$570		Add to Cart
BHA21000877-9	PB9971-HRP	100 ug	HRP	$570		Add to Cart
BHA21000877-10	PB9971-APC	100 ug	APC	$670		Add to Cart
BHA21000877-11	PB9971-PE	100 ug	PE	$670		Add to Cart
BHA21000877-12	PB9971-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000877-13	PB9971-carrier-free	100 ug	carrier-free	$370		Add to Cart

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