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Home / Primary Antibodies / Polyclonal Antibodies

Anti-AASS Antibody Picoband®

SKU : BHA21003645

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Mfr.No.	A07302-3, A07302-3-10ug, A07302-3-Biotin, A07302-3-Cy3, A07302-3-Dylight488, A07302-3-Dylight550, A07302-3-Dylight594, A07302-3-FITC, A07302-3-HRP, A07302-3-APC, A07302-3-PE, A07302-3-iFluor647, A07302-3-carrier-free
Alternative Names	mesoderm posterior bHLH transcription factor 1
Background	Alpha-aminoadipic semialdehyde synthase is an enzyme encoded by the AASS gene in humans and is involved in their major lysine degradation pathway. This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-AASS Antibody Picoband® catalog # A07302-3. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patteing of the somites by participating in distinct Notch pathways.
Host	Rabbit
Immunogen Region	E.coli-derived human AASS recombinant protein (Position: E37-N865).
Isotype	Rabbit IgG
Molecular Weight	102 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Mesoderm posterior protein 1; Class C basic helix-loop-helix protein 5; bHLHc5; MESP1; BHLHC5
Tissue Specificity	Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9UDR5
Gene Id	10157
Gene Name	AASS
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25 ug/ml, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Dancis, J., Hutzler, J., Woody, N. C., Cox, R. P. Multiple enzyme defects in familial hyperlysinemia. Pediat. Res. 10: 686-691, 1976. 2. Houten, S. M., te Brinke, H., Denis, S., Ruiter, J. P. N., Knegt, A. C., de Klerk, J. B. C., Augoustides-Savvopoulou, P., Haberle, J., Baumgartner, M. R., Coskun, T., Zschocke, J., Sass, J. O., Poll-The, B. T., Wanders, R. J. A., Duran, M. Genetic basis of hyperlysinemia. Orphanet J. Rare Dis. 8: 57, 2013. Note: Electronic Article. 3. Sacksteder, K. A., Biery, B. J., Morrell, J. C., Goodman, B. K., Geisbrecht, B. V., Cox, R. P., Gould, S. J., Geraghty, M. T. Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia. Am. J. Hum. Genet. 66: 1736-1743, 2000.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003645-1	A07302-3	-	100 ug	$370		Add to Cart
BHA21003645-2	A07302-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21003645-3	A07302-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003645-4	A07302-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003645-5	A07302-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003645-6	A07302-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003645-7	A07302-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003645-8	A07302-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21003645-9	A07302-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21003645-10	A07302-3-APC	APC	100 ug	$670		Add to Cart
BHA21003645-11	A07302-3-PE	PE	100 ug	$670		Add to Cart
BHA21003645-12	A07302-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003645-13	A07302-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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