Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Categories
Primary Antibodies
Cellular Localization
Cell Junction, Tight Junction
Clonality
polyclonal
Description
Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Host
Rabbit
Immunogen
angiomotin like 1
Isotype
IgG
Molecular Weight
107 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cell junction, Tight junction
Synonyms
AMOTL1, Angiomotin like protein 1, angiomotin like 1, JEAP
Antigen
AMOTL1
Uniprot
Q8IY63
Gene Id
154810
Research Area
Developmental biology, Cardiovascular
Weight
107kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)