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Home / Primary Antibodies / Polyclonal Antibodies

AKR1C4 antibody

SKU : BHA10800261

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Mfr.No.	FNab00263
Alternative Names	AKR1C4 ; HAKRA ; CHDR ; 3alphaHSD1 ; Chlordeconereductase
Background	Catalyzes the transformation of the potent androgen dihydrotestosterone(DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol(3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone(kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm
Clonality	polyclonal
Description	Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha- androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20- alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Host	Rabbit
Immunogen	aldo-keto reductase family 1, member C4(chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
Isotype	IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm
Synonyms	AKR1C4, HAKRA, CHDR, 3 alpha HSD1, Chlordecone reductase

Antigen	AKR1C4
Uniprot	P17516
Gene Id	1109
Research Area	Metabolism
Weight	37kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF

Dilution

WB	1:1000-1:10000
IF	1:10-1:100

Tested Application

WB: 1:1000-1:10000; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800261	FNab00263	100ug	$260		Add to Cart

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