A Disintegrin and Metalloproteinase Domain 2, also known as FTNB or PH30, is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Burkin et al.(1997) used fluorescence in situ hybridization to map the FTNB gene to 8p11.2.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the C-terminus of human A Disintegrin and Metalloproteinase Domain 2 (VLIAIMVKVNFQRKK) was used as the immunogen for this ADAM2 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
ADAM2
Uniprot
Q99965
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the ADAM2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.