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Home / Primary Antibodies / Polyclonal Antibodies

ACTN2 Antibody / Alpha Actinin 2 / Sarcomeric Alpha Actinin

SKU : BHA17122803

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NSJ Bioreagents

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Mfr.No.	RQ6542
Clonality	Polyclonal (rabbit origin)
Description	Alpha-actinin 2 is a protein which in humans is encoded by the ACTN2 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An E. coli-derived human protein (amino acids E567-E696) was used as the immunogen for the ACTN2 antibody.
Isotype	Rabbit IgG
Species Reactivity	Human, Mouse, Rat
Note	Optimal dilution of the ACTN2 antibody should be determined by the researcher.

Uniprot	P35609

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the ACTN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, FACS, Direct ELISA
Description	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122803	RQ6542	100ug	$439		Add to Cart

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