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Home / Primary Antibodies / Polyclonal Antibodies

ABCB1 Antibody / P Glycoprotein / MDR1

SKU : BHA17119168

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NSJ Bioreagents

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Mfr.No.	RQ6755
Clonality	Polyclonal (rabbit origin)
Description	P-GP, also called ABCB1, MDR1 and PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood�brain barrier.
Host	Rabbit
Immunogen Region	Amino acids TKEALDESIPPVSFWRIMK from the human protein were used as the immunogen for the ABCB1 antibody.
Isotype	Rabbit IgG
Reactivity	Human
Recombinant	No

Antigen	P Glycoprotein
Uniprot	P08183

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the ABCB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	FACS, IF, WB
Dilution	Western blot: 1-2ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119168	RQ6755	100ug	$439		Add to Cart

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