Angio-associated migratory cell protein is in humans is encoded by the AAMP gene. It is mapped to 2q35. AAMP is an immunoglobulin-type protein which is found to be expressed strongly in endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics. It has been demonstrated that an AAMP peptide containing the putative heparan sulfate-binding domain binds to heparin and mediates heparin-sensitive cell adhesion. It plays a role in angiogenesis and cell migration. In smooth muscle cell migration, it may act through the RhoA pathway.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 235-434) was used as the immunogen for this AAMP antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
AAMP
Gene Id
14
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the AAMP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
FACS, IHC-P, IF, WB, ICC
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunofluorescence: 2-4ug/ml,Flow cytometry: 1-3ug/million cells