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Home / Antibodies

PINK1 Antibody (F53741)

SKU : BHA17119850

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Mfr.No.	F53741-0.1ML
Clonality	Monoclonal (mouse origin)
Description	PINK1 protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form. (UniProt)
Formulation	In ascites with 0.09% sodium azide
Host	Mouse
Immunogen Region	Recombinant protein was used to produced this PINK1 antibody.
Isotype	Mouse IgG1
Species Reactivity	Human, Mouse
Note	Titration of the PINK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	Q9BXM7

Format	Ascites
Purity	Ascites
Storage	Aliquot the PINK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ELISA
Description	Western blot: 1:500-1:2000,IHC (Paraffin): 1:10-1:50

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119850	F53741-0.1ML	0.1 ml	$389		Add to Cart

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