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AFFINITY BIOSCIENCES LTD
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AFFINITY BIOSCIENCES LTD
view supplier detailsCredit card payments now incur a 3% fee.
| Mfr.No. | AF3232 |
| Alternative Names | 18 kDa phosphoprotein ; CFL 1 ; CFL ; CFL1 ; COF1_HUMAN ; Cofilin 1 ; Cofilin 1 non muscle ; Cofilin ; Cofilin non muscle isoform ; Cofilin-1 ; epididymis secretory protein Li 15 ; HEL-S-15 ; non-muscle isoform ; p18 ; |
| Categories | Primary Antibodies ; Phospho Antibodies |
| Clonality | polyclonal |
| Description | cofilin 1 a cytoskeletal protein that controls actin depolymerization. Has a 5-10-fold higher affinity for ATP-actin monomers than cofilin-1. May promote filament assembly rather than disassembly. Two alternatively spliced variants are described. |
| Immunogen | A synthesized peptide derived from human Cofilin around the phosphorylation site of Serine 3. |
| Molecular Weight |
Observed Mol.Wt.: 19kDa. Predicted Mol.Wt.: 19kDa. |
| Reactivity | Rat, Mouse, Human |
| Specificity | Phospho-Cofilin (Ser3) Antibody detects endogenous levels of Cofilin only when phosphorylated at Serine 3. |
| Subcellular Location | Nucleus matrix. Cytoplasm > cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide. |
| Antigen | Phospho-Cofilin (Ser3) | |||||||||||||||||||||||||||||||||
| Uniprot | P23528 | |||||||||||||||||||||||||||||||||
| Gene Id | 1072 | |||||||||||||||||||||||||||||||||
| Sequence |
|
| Concentration | 1mg/ml |
| Format | Liquid |
| Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
| Storage Condition | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
| Applications | IF/ICC, WB, IHC, ELISA |
| Dilution | WB 1:500-1:2000 IHC 1/200 IF/ICC 1/200, ELISA(peptide) 1:20000-1:40000 |
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| SKU | Supplier No. | Size | Your price | Quantity | |
|---|---|---|---|---|---|
| BHA12903145 | AF3232 | 100ul | $280 |
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| BHA12903145 | AF3232 | 200ul | $350 |
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