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Home / Primary Antibodies / Polyclonal Antibodies

NR2C1 Antibody (CSB-PA016051ESR1HU)

SKU : BHA10518321

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA016051ESR1HU
Alternative Names	Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2), NR2C1, TR2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Host	Rabbit, Rabbit
Immunogen	Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA), Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Nucleus, PML body, Nucleus, Nucleus, PML body

Antigen	NR2C1, NR2C1
Uniprot	P13056
Database Links	HGNC:7971 OMIM:601529 KEGG:hsa:7181 STRING:9606.ENSP00000333275 UniGene:Hs.108301 , HGNC:7971 OMIM:601529 KEGG:hsa:7181 STRING:9606.ENSP00000333275 UniGene:Hs.108301
Function	Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Protein Families	Nuclear hormone receptor family, NR2 subfamily, Nuclear hormone receptor family, NR2 subfamily
Research Area	Epigenetics and Nuclear Signaling, Epigenetics and Nuclear Signaling

Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form	Liquid
Format	Liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified, Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-2000
IHC	1:20-1:200

Tested Application

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10518321	CSB-PA016051ESR1HU	50ul	$166		Add to Cart
BHA10518321	CSB-PA016051ESR1HU	100ul	$299		Add to Cart

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