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Home / Primary Antibodies / Monoclonal Antibodies

VEGFR2 Antibody / VEGF Receptor 2 / KDR

SKU : BHA17117814

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NSJ Bioreagents

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Mfr.No.	V8272, V8272-20UG, V8272-100UG
Clonality	Monoclonal
Description	This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Formulation	0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Rat
Immunogen Region	Recombinant full-length Mouse VEGFR2 protein was used as the immunogen for this VEGFR2 antibody.
Isotype	IgG1,kappa
Predicted Reactivity	Mouse
Reactivity	Mouse
Recombinant	No

Antigen	VEGF Receptor 2
Uniprot	P35918
Clone No	DC101

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the VEGFR2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	Neutralizing, Blocking, Inhibition, WB
Dilution	Western blot (Non-reducing): 2-5ug/ml,Blocks binding of VEGF to VEGF-R2,Inhibits VEGF-induced signalingformat),Blocks tumor growth in mice

Product Manual	Data Sheet

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