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Home / Primary Antibodies / Monoclonal Antibodies

Uroplakin III

SKU : BHA15100468

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BioGenex Laboratories

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Mfr.No.	AMB38-5M
Clonality	Monoclonal
Description	Uroplakins IIIa (UPIIIa) belongs to a family of transmembrane proteins Uroplakins that are specific differentiation products of urothelial cells. It is a component of the asymmetric unit membrane (AUM) and is a highly specialized bio-membrane made by terminally differentiated urothelial cells. It plays a major role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPIIIa contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. It is present in the urothelial surface membrane of human renal pelvis, ureter, bladder and urethra. UPIIIa is specific for tumors of urothelial origin and, used in combination with other markers in the diagnosis of primary and metastatic tumors. Loss of Uroplakin IIIa expression in bladder cancers has been associated with higher grade, muscle-invasive cancer and lymphovascular invasion. Uroplakin III may be used in a panel of antibodies including GATA3, p63 and S100P.
Host	Mouse
Isotype	IgG2a
Reactivity	Human
Species	Mouse

Clone No	C-6
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMB38-5M	AMB38-5M	6 mL	$251		Add to Cart
AMB38-10M	AMB38-10M	100 tests - i6000	$469		Add to Cart
AXB38-50D	AXB38-50D	50 tests - Xmatrx	$263		Add to Cart
AXB38-YCD	AXB38-YCD	160 tests - Xmatrx	$642		Add to Cart
MUB38-UC	MUB38-UC	1ml Conc	$514		Add to Cart
MUB38-5UC	MUB38-5UC	0.5ml Conc	$359		Add to Cart

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