The protein encoded by the TH gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome.
Formulation
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host
Rabbit
Immunogen Region
A synthetic peptide specific to human Tyrosine Hydroxylase / TH was used as the immunogen for the Tyrosine Hydroxylase antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Subcellular Location
Nuclear, cytoplasmic, cell membrane
Antigen
TH
Uniprot
P07101
Clone No
ECA-20
Format
Purified
Purification
Affinity purified
Storage
Store the Tyrosine Hydroxylase antibody at -20°C.
Applications
IHC-P, WB
Dilution
Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:50-1:200