Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor(SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer(NK) cells.
Categories
Primary Antibodies
Clonality
monoclonal
Description
Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N- ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.
Host
Mouse
Immunogen
syntaxin binding protein 2
Isotype
IgG2a
Molecular Weight
66 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
UNC18B
Uniprot
Q15833
Gene Id
6813
Clone No
2C7
Research Area
Neuroscience
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)