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Home / Primary Antibodies / Monoclonal Antibodies

Smoothelin

SKU : BHA15100470

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BioGenex Laboratories

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Mfr.No.	AMB40-5M
Clonality	Monoclonal
Description	Smoothelin is a constituent of the smooth muscle cell cytoskeleton protein exclusively found in differentiated smooth muscle cells (SMC). Smoothelin associates with actin stress fibers but does not interact with desmin. A short and long isoforms of smoothelin are produced by alternative splicing. The short isoform is expressed in visceral muscle tissue, including intestine and stomach, but not in brain, while the long isoform is expressed in all vascularized organs. In the vascular system, smoothelin expression is limited to large veins and arteries capable of pulsatile contraction. Cells with SMC-like characteristics, such as myofibroblasts and myoepithelial cells, as well as skeletal and cardiac muscle do not contain smoothelin. Smoothelin antibody has been reported to be a useful tool in monitoring SMC differentiation; and may aid in the distinction of terminally differentiated smooth muscle cells, smooth muscle neoplasms of the gastrointestinal tract and the staging of bladder carcinoma.
Host	Mouse
Isotype	IgG2b
Reactivity	Human
Species	Mouse

Clone No	C-8
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMB40-5M	AMB40-5M	6 mL	$304		Add to Cart
AMB40-10M	AMB40-10M	100 tests - i6000	$569		Add to Cart
AXB40-50D	AXB40-50D	50 tests - Xmatrx	$320		Add to Cart
AXB40-YCD	AXB40-YCD	160 tests - Xmatrx	$779		Add to Cart
MUB40-UC	MUB40-UC	1ml Conc	$624		Add to Cart
MUB40-5UC	MUB40-5UC	0.5ml Conc	$437		Add to Cart

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