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Home / Primary Antibodies / Monoclonal Antibodies

RPA70 Antibody / RPA1

SKU : BHA17109302

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NSJ Bioreagents

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Mfr.No.	RQ4489
Clonality	Monoclonal
Description	As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. (UniProt)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide from human RPA70 was used as the immunogen for the RPA70 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	Yes

Antigen	RPA70
Uniprot	P27694
Clone No	BB-18

Format	Purified
Purification	Protein A affinity
Storage	Store the RPA70 antibody at -20°C.

Applications	WB
Dilution	Western blot: 1:500-1:1000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109302	RQ4489	100ul	$439		Add to Cart

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