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Home / Primary Antibodies / Monoclonal Antibodies

RBP4 Monoclonal Antibody (CSB-MA070501A0m)

SKU : BHA10560868

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA070501A0m
Alternative Names	Plasma retinol-binding protein, PRBP, RBP, RBP4, PRO2222
Categories	Primary Antibodies
Clonality	monoclonal
Description	Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
Host	Mouse
Immunogen	Recombinant Human Retinol-binding protein 4 protein
Isotype	IgG1
Raised In	mouse
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
Species	Homo Sapiens (Human)
Specificity	specific for native and denatured forms

Antigen	RBP4 Monoclonal
Clone No	6A1C2

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Description	specific for native and denatured forms
Form	liquid
Format	liquid
Purification	>95%,Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution

WB	1:500-1:5000
IHC	1:50-1:500

Tested Application

ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560868	CSB-MA070501A0m	50ug	$210		Add to Cart
BHA10560868	CSB-MA070501A0m	100ug	$350		Add to Cart

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