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Home / Primary Antibodies / Monoclonal Antibodies

PLK1 Antibody

SKU : BHA17110158

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NSJ Bioreagents

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Mfr.No.	RQ5512
Clonality	Monoclonal
Description	Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase1) gene. Plk1 is an early trigger for G2/M transition. It supports the functional maturation of the centrosome in late G2/early prophase and establishment of the bipolar spindle. Also, Plk1 phosphorylates and activates cdc25C, a phosphatase that dephosphorylates and activates the cyclinB/cdc2 complex. Studies have shown that the loss of PLK1 expression can induce pro-apoptotic pathways and inhibit growth. Based on yeast and murine studies of meiosis, human PLK1 may also have a regulatory function in meiosis.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Mouse
Immunogen Region	A human recombinant protein (amino acids K86-N430) was used as the immunogen for the PLK1 antibody.
Isotype	IgG2b
Predicted Reactivity	Human, Mouse, Rat, Monkey
Reactivity	Human, Mouse, Rat, Monkey
Recombinant	No

Antigen	PLK1
Uniprot	P53350
Clone No	6D11

Buffer	Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Format	Antigen affinity purified
Purification	Affinity purified
Storage	After reconstitution, the PLK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110158	RQ5512	100ug	$439		Add to Cart

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