PDCD10, also named CCM3 and TFAR15, belongs to the PDCD10 family. PDCD10 promotes cell proliferation, increases MAPK activity and modulates apoptotic pathways. PDCD10 is important for cell migration and for normal structure and assembly of the Golgi complex. PDCD10 is required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development, moreover, defects in PDCD10 showed abnormal cardiovascular development.
Clonality
monoclonal
Host
Mouse
Immunogen
programmed cell death 10
Immunogen Region
programmed cell death 10
Isotype
IgG1
Molecular Weight
25-30KD
Reactivity
Human
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Synonyms
CCM3, PDCD10, programmed cell death 10, TFAR15
Uniprot
Q9BUL8
Gene Id
11235
Clone No
2A8
Research Area
Developmental biology, Immunology, Signal Transduction, Neuroscience
Form
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:50-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10302.pdf" target="_blank">Data Sheet</ a>