The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. (RefSeq)
Formulation
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host
Rabbit
Immunogen Region
A synthetic peptide specific to human PCNA was used as the immunogen for the PCNA antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse
Reactivity
Human, Mouse
Recombinant
No
Subcellular Location
Nuclear
Antigen
PCNA
Uniprot
P12004
Clone No
DO-16
Format
Purified
Purification
Affinity purified
Storage
Store the PCNA antibody at -20°C.
Applications
IHC-P, WB
Dilution
Western blot: 1:3000-1:10000,Immunohistochemistry (FFPE): 1:50-1:200