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Home / Primary Antibodies / Monoclonal Antibodies

p27Kip1 Antibody

SKU : BHA17103870

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NSJ Bioreagents

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Mfr.No.	R30066
Clonality	Monoclonal
Description	P27(kip1), also known as cyclin dependent kinase inhibitor 1B(CDKN1B), is a major target of AFX-like forkhead proteins. CDKN1B(p27) belongs to the Cip/Kip family and functions as an important cell cycle gatekeeper. Phosphorylation leads to the ubiquitination and degradation of CDKN1B. P27(kip1) mapped to 12p13. An increase in p27 causes proliferating cells to exit from the cell cycle, and a decrease in p27 is necessary for quiescent cells to resume division. Abnormally low amounts of p27 are associated with pathological states of excessive cell proliferation, especially cancers. Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells.
Formulation	0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Host	Mouse
Immunogen Region	recombinant rodent p27Kip1 protein was used as the immunogen for this p27Kip1 antibody.
Isotype	IgG1
Predicted Reactivity	Human, mouse, rat
Reactivity	mouse, rat, Human
Recombinant	No

Antigen	p27Kip1
Gene Id	1027
Clone No	DCS-72

Format	Ascites
Purification	Ascites
Storage	After reconstitution, the p27Kip1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	ICC, WB
Dilution	Western blot: 2-4ug/ml,Immunocytochemistry: Suitable

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17103870	R30066	100ug	$439		Add to Cart

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