Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Formulation
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host
Rabbit
Immunogen Region
A synthetic peptide specific to human OPA1 was used as the immunogen for the OPA1 antibody.