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Home / Primary Antibodies / Monoclonal Antibodies

NOX4 Antibody / NADPH oxidase 4

SKU : BHA17109295

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NSJ Bioreagents

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Mfr.No.	RQ4482
Clonality	Monoclonal
Description	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity. (UniProt)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide from human NOX4 was used as the immunogen for the NOX4 antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	Yes
Subcellular Location	Cytoplasm (ER membrane)

Antigen	NOX4
Uniprot	Q9NPH5
Clone No	E-14

Format	Purified
Purification	Protein A affinity
Storage	Store the NOX4 antibody at -20°C.

Applications	IHC-P, WB
Dilution	Western blot: 1:500-1:2000,Immunohistochemisty (FFPE): 1:50-1:200,Immunofluorescence: 1:50-1:200

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109295	RQ4482	100ul	$439		Add to Cart

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