Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. The NEFM gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. (RefSeq)
Formulation
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host
Rabbit
Immunogen Region
A synthetic peptide specific to human NEFM / Neurofilament Medium was used as the immunogen for the NF-M antibody.