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Home / Primary Antibodies / Monoclonal Antibodies

NCAM1/CD56 antibody

SKU : BHA10805567

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Mfr.No.	FNab05575
Background	Neural cell adhesion molecule 1(NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin(Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurones, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alteative splicing of mRNA(PMID: 9696812). The glycosylphosphatidylinositol(GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronection-type III repeats(FNIII). All three forms can be posttranslationally modified by addition of polysialic acid(PSA)(PMID: 14976519). Several other isofroms have also been described(PMID: 1856291).
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	neural cell adhesion molecule 1
Isotype	IgG2a
Molecular Weight	140 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	CD56, MSK39, N CAM 1, NCAM, NCAM 1, NCAM1

Uniprot	P13591
Clone No	0D10
Research Area	Developmental biology, Signal Transduction, Immunology, Cancer, Stem Cells, Neuroscience

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:1000-1:10000; IHC: 1:200-1:1000

Manual	FNab05575.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805567	FNab05575	100ug	$280		Add to Cart

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